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Molecular structurePubMed
injectableanabolic
Drostanolone Propionate
MasteronMast PDrostanolone
62
Anabolic Ratio
25
Androgenic Ratio
2.5d
Half-Life
DHT-derivative with anti-estrogenic properties (weak aromatase inhibitor). Produces muscle density and hardness with no water retention. Best at low body fat. Often used as a 'dry' compound finishing cycle.
Mechanism of Action
Does not aromatize. Acts as a mild competitive aromatase inhibitor, lowering estrogen levels. Binds SHBG, freeing more free testosterone. DHT-derived, so minimal 5α-reduction, but androgenic at scalp.
Typical Dosing
200 mg
low / week
400 mg
moderate / week
700 mg
high / week
⚠ Warning Flags
- •Hair loss acceleration in DHT-sensitive individuals
Effect Profile
Muscle Protein Synthesis4Low
Nitrogen Retention4Low
Strength Gains5Moderate
Red Blood Cell Production2Minimal
Fat Loss6Moderate
Glycogen Storage3Low
Recovery Speed4Low
Collagen Synthesis3Low
Side Effect Profile
Hormonal Suppression4Low
Estrogenic Effects1Minimal
Androgenic Effects5Moderate
Cardiovascular Strain3Low
Liver Stress1Minimal
Insulin Resistance1Minimal
Mood Changes3Low
Prostate Risk3Low
Research Studies
Pharmacology of anabolic steroids
Kicman AT. · 2008
Review documents drostanolone's unique anti-estrogenic mechanism and favorable side-effect profile, explaining its use as a finishing compound.