Norethandrolone
One of the first synthetic anabolic steroids developed (1956), predating Dianabol. A 19-nor compound (related to nandrolone) with an ethyl group at C17. Historically used for anemia and muscle wasting. Notable for being the first synthetic progestogen to show potent anabolic properties. Now largely replaced by safer alternatives.
Mechanism of Action
19-nortestosterone derivative — reduced androgenicity due to 5α-reduction to a less active metabolite in androgenic tissue. Moderate progestogenic activity (as a 19-nor). 17α-ethyl group provides oral bioavailability. Aromatizes to 17α-ethyl estradiol. Similar suppression profile to nandrolone.
Typical Dosing
⚠ Warning Flags
- •Largely obsolete — replaced by safer 19-nor compounds
- •Oral 17α-alkylated hepatotoxicity
- •Prolactin elevation risk (19-nor class)
Effect Profile
Side Effect Profile
Research Studies
The myotrophic and androgenic effects of 17-ethyl-19-nortestosterone and related compounds
Saunders FJ, Drill VA. · 1956
Original pharmacological characterization of norethandrolone, establishing its anabolic-to-androgenic differentiation (Hershberger assay) and superior anabolic selectivity versus testosterone — one of the foundational papers in AAS pharmacology.