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oralanabolic

Oxandrolone

AnavarVarOxandrin
322
Anabolic Ratio
24
Androgenic Ratio
0.375d
Half-Life

One of the most clinically used anabolic steroids in the world. Extremely mild androgenic profile. Used medically for burn recovery, HIV wasting, pediatric growth. Minimal liver stress for an oral. Expensive.

Mechanism of Action

High AR binding affinity. Does NOT aromatize. Minimal 5α-reduction activity. Increases protein synthesis and nitrogen retention at low androgenic cost. Modest HPTA suppression relative to other compounds.

Oxandrolone molecule
Molecular structure

Typical Dosing

140 mg
low / week
280 mg
moderate / week
560 mg
high / week

⚠ Warning Flags

  • Oral — lipid impact (LDL↑, HDL↓) despite mild liver profile
  • Counterfeits are very common

Effect Profile

Muscle Protein Synthesis
5Moderate
Nitrogen Retention
6Moderate
Strength Gains
6Moderate
Red Blood Cell Production
2Minimal
Fat Loss
5Moderate
Glycogen Storage
4Low
Recovery Speed
5Moderate
Collagen Synthesis
4Low

Side Effect Profile

Hormonal Suppression
4Low
Estrogenic Effects
1Minimal
Androgenic Effects
2Minimal
Cardiovascular Strain
4Low
Liver Stress
3Low
Insulin Resistance
2Minimal
Mood Changes
2Minimal
Prostate Risk
2Minimal

Research Studies

Effects of androgen therapy on adipose tissue and metabolism in older men

Schroeder ET, et al. · 2005

PubMed

6 weeks of oxandrolone increased muscle strength and lean mass in healthy older men, with minimal side effects confirming the compound's favorable safety profile.

Oxandrolone significantly improves hepatic dysfunction in severely burned children

Jeschke MG, et al. · 2007

PubMed

Oxandrolone reduced catabolism and improved lean mass in severely burned pediatric patients, validating its medical use and documenting safety at therapeutic doses.

Oxandrolone, an anabolic steroid, significantly increases the rate of weight gain in the recovery phase after major burns

Demling RH, DeSanti L. · 1997

PubMed

Burn patients receiving oxandrolone regained lean mass 2× faster than controls, demonstrating powerful anti-catabolic effects.