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Molecular structurePubMed
injectableandrogen
Testosterone Cypionate
Test CTC
100
Anabolic Ratio
100
Androgenic Ratio
8d
Half-Life
Nearly identical to Testosterone Enanthate in effects and side effects. Slightly longer half-life (8 days). The most commonly prescribed TRT form in the USA.
Mechanism of Action
Same as Testosterone Enanthate — AR agonist, aromatizes to estradiol, 5α-reduces to DHT. The cypionate ester is slightly longer, leading to marginally slower release.
Typical Dosing
250 mg
low / week
500 mg
moderate / week
1000 mg
high / week
Effect Profile
Muscle Protein Synthesis7High
Nitrogen Retention7High
Strength Gains7High
Red Blood Cell Production5Moderate
Fat Loss4Low
Glycogen Storage6Moderate
Recovery Speed7High
Collagen Synthesis5Moderate
Side Effect Profile
Hormonal Suppression8Very High
Estrogenic Effects6Moderate
Androgenic Effects6Moderate
Cardiovascular Strain5Moderate
Liver Stress1Minimal
Insulin Resistance2Minimal
Mood Changes4Low
Prostate Risk5Moderate
Research Studies
Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men
Wang C, et al. · 2000
TRT improved lean mass and sexual function, establishing cypionate as a clinically validated testosterone replacement option.